LIFECODES Cytokine SNP Typing
The LIFECODES Cytokine SNP Typing kit utilizes the Luminex xMAP technology and an SSO methodology to identify a number of cytokine polymorphisms that either increase or decrease the level of the individual cytokines. The kit was designed to detect those cytokine polymorphisms identified by the 13th International Workshop and Congress as having a potential role in transplantation.
The Cytokine SNPs detected by this kit are:
| Cytokine Multiplex I |
|
Cytokine
|
Function
|
SNP Alleles
|
|
IL-6
|
Pro and Anti-inflammatory
|
C/G at -174
|
|
TNF-α
|
Pro-inflammatory
|
G/A at -308
G/A at -238
|
|
IL-10
|
Anti-inflammatory
|
G/A at -1082
C/T at -819
C/A at -592
|
|
IFN-γ
|
Pro-inflammatory
|
A/T at +874
|
|
Cytokine Multiplex II
|
|
Cytokine
|
Function
|
SNP Alleles
|
|
IL-1 Family
|
Pro-inflammatory
|
|
|
IL-1α
|
|
T/C at -889
|
|
IL-1β
|
|
C/T at -511
T/C at +3954 (3962)
|
|
IL-1R
|
|
C/T at pstI 1970
|
|
IL-1Ra
|
|
C/T at mspal 11100
|
|
IL-12B
|
Pro-inflammatory
|
A/C at -1188
|
|
TGFb Mix
|
|
Cytokine
|
Function
|
Alleles
|
|
TGF-β
|
Anti-inflammatory
|
C/T at +869
C/G at +915
|
- Premade master mix includes primers, dNTPs and PCR buffer eliminating extra steps and consumables
- Homogeneous assay eliminates the need for centrifugation and wash steps saving time and reducing the chances of pipeting errors
|
Catalog Number
|
Description
|
|
345110
|
LIFECODES Cytokine SSO Typing Kit
(20 tests/kit) For Research Use Only
|
