A total of 27 mutations in 10 different diseases common to Ashkenazi Jews are detected in four multiplexed assays, developed using the reliable and accurate ARMS™ technology.
Each assay enables multiple detection of frequent mutations common in Ashkenazi Jews. Each is also separately available as an ELUCIGENE kit to provide complete flexibility for the different needs of mutation screening programs.
Please note: Licences for the in vitro diagnostic analysis of gene mutations detected by these reagents may be required and are the responsibility of the reagent purchaser.
Ashplex 1
Ashplex 1 detects eight mutations in four of the most common diseases of Ashkenazi Jews and is particularly suited to routine mutation screening for Tay Sachs Disease, Familial Dysautonomia, Canavan Disease and Fanconi Anemia.
• How to Order • Cat. No. AS008B2
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Ashplex 2
Ashplex 2 detects seven mutations in four different diseases common to Ashkenazi Jews and can be used for routine mutation detection in Mucolipidosis IV, Niemann-Pick Disease, Glygogen Storage Disease and Blooms Syndrome.
• How to Order • Cat. No. SS007B2
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Gaucher
Gaucher Disease is the most common of the ten diseases tested by ELUCIGENE products, with a carrier frequency of 1 in 13 in Ashkenazi Jews. The ELUCIGENE Gaucher kit reliably detects five mutations in the glucocerebrosidase gene that cause Gaucher Disease.
• How to Order • Cat. No. GD005B2
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CF7
ELUCIGENE CF7 detects the seven most common CFTR mutations that are responsible for 97% of cystic fibrosis chromosomes in Ashkenazi Jews.
• How to Order • Cat. No. CF007B4
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CF-MEP
ELUCIGENE CF-MEP detects five mutations in the CFTR gene that are particularly common in Sephardic Jews of middle-eastern origin.
When used together with ELUCIGENE CF7 a total of 11 different mutations can be identified giving an excellent coverage in Jews of various ethnic backgrounds.
• How to Order • Cat. No. YF005B4
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