Alpha –1– Antitrypsin (AAT) deficiency is an autosomal recessive disorder that is virtually confined to Caucasians of European descent and is the most common genetic cause of liver disease in children and emphysema in adults.
AAT
ELUCIGENE AAT provides laboratories with a simple and robust test for the routine detection of the S and Z variants of the AAT gene that are associated with AAT deficiency. The kit provides a useful alternative to the labour intensive and highly skilled iso-electric focusing (IEF) method of analysis of AAT variants.
